Well, that went poorly. The Virtualbox software caused my PC to hiccup at the USB ports every so often and the mouse would stop responding. It only happened when Virtualbox wasn't running which is odd to say the least. I uninstalled it last night and my mouse hasn't stopped responding at all since.
As soon as I installed VB I heard duhn-dunk (the windows sound you hear when you unplug something USB) and my mouse would quit working for a bit and then pick back up. When I was in 8 on VB it wouldn't do it. Now that I've uninstalled VB it doesn't do it except in Skyrim (yeah I reinstalled it) which is really pissing me off.