I don't know that it will necessarily affect many here, but the new chips are going to start implementing hardware level Digital Rights Management (DRM). Personally this concerns me because I use my current computer as a DVR/PVR/HTPC (call it what you want, it's all the same) as well as normal gaming, etc. I think it's part of Intels Viiv. It's not something they want you to know, but there you go.
Other than that, I'm very excited about these new systems coming out. My plan was to upgrade the summer, but I may have to hold off a little longer and do it this fall when more options are available.