If you're a McAfee user and are running Windows XP, make sure you update to the latest version of the DAT file (5959) if you want to avoid any issues, some of which could be severe. Yesterday, or late Monday night, McAfee released its 5958 DAT file which effectively borked some XP installations, leaving the user with nothing more than a major headache.
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You can read the rest of our post here.