I think Winamp is the primary open application. I've hooked up the wireless music system to another PC and a laptop. and the remote (i.e. pause and skip track) doesn't work on either of those as well. Maybe the product is defective, but I'm in Canada and I ordered it from the states, and returning it is too much of a hassle and too costly. I'm still pretty happy with it. It'll due until a better model comes out. This one is seems to be a no-frills item meant mostly to test the market for this kind of product (that's my guess).